X. Dong

Aerobic methane production by methylotrophic Methylotenera in groundwater

The paper identifies Methylotenera ecotypes in methane-rich groundwater that use methylphosphonate for aerobic methane production, suggesting phosphate limitation in these environments.

Illuminating microbial phosphorus cycling in deep-sea cold seep sediments using protein language models

This study uses a protein language model to discover new phosphorus-cycling protein families in deep-sea cold seep sediments, revealing novel microbial processes and ecological roles.

Uncovering the hidden RNA virus diversity in Lake Nam Co: evolutionary insights from an extreme high-altitude environment

This study identifies 742 RNA virus species in Lake Nam Co, revealing novel viral groups and evolutionary adaptations in an extreme high-altitude environment.

Wetland tree barks are dynamic hotspots for microbial trace gas cycling

The paper identifies microbial communities in wetland tree barks that mediate methane and hydrogen cycling, showing they can both mitigate and emit climate-active gases.

Viral diversiy within marine biofilms and their potential roles in microbially influenced corrosion

This study analyzes viral communities in marine biofilms on 8 materials to explore their roles in microbially influenced corrosion, finding viruses influence corrosion through interactions with corrosive microbes.

Cold seeps are hotspots of deep-sea nitrogen-loss driven by microorganisms across 21 phyla

This study identifies cold seeps as significant nitrogen-loss hotspots, revealing diverse microbial communities and active nitrogen-loss genes across multiple phyla.

Mitochondrial DNA is a sensitive surrogate and oxidative stress target in oral cancer cells

This study develops a method to quantify mtDNA damage, repair, and copy number changes in oral cancer cells under oxidative stress and finds differential responses compared to normal cells.

Complete list of canonical post-transcriptional modifications in the Bacillus subtilis ribosome and their link to RbgA driven large subunit assembly

The paper identifies 25 rRNA modification sites in B. subtilis and links them to RbgA-dependent large subunit assembly.

Fast adaptive super-resolution lattice light-sheet microscopy for rapid, long-term, near-isotropic subcellular imaging

This paper introduces Meta-rLLS-VSIM, a super-resolution microscopy technique that achieves near-isotropic resolution with reduced training time and data requirements.

Domain consolidation in Bacterial 50S assembly revealed by Anti-Sense Oligonucleotide Probing

The paper uses anti-sense oligonucleotides to disrupt RNA interactions in bacterial ribosome assembly, revealing intermediate structures and domain consolidation during RNP formation.

Deciphering the Transcription Factor Landscape in Neuroendocrine Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

This study identifies lineage-specific transcription factor profiles in prostate cancer progression, revealing dynamic shifts during NE transdifferentiation and proposing a three-phase model.

Assembly of the Bacterial Ribosome with Circularly Permuted rRNA

This study investigates bacterial ribosome assembly using circularly permuted rRNAs, revealing conserved assembly routes and domain association order.

Extracellular electron transfer drives efficient H2-independent methylotrophic methanogenesis by Methanomassiliicoccus, a seventh order methanogen

This study shows Methanomassiliicoccus uses extracellular electron transfer for efficient methylotrophic methanogenesis, enhancing methane production in coculture with electrogenic bacteria.

Efficient differentiation of human retinal pigment epithelium cells from chemically induced pluripotent stem cells

This study develops a chemical method to generate hCiPSCs and demonstrates their efficient differentiation into RPE cells for AMD treatment.

MICROCOSM FABRICATION PLATFORM FOR LIVE MICROSCOPY OF PLANT-SOIL SYSTEMS

The paper develops a microcosm fabrication platform for live microscopy of plant-soil systems, enabling controlled water content and observation of root-soil interactions.

Efficient cloning of genes for wheat yield component traits from QTLs via sequencing of the RIL population

This study develops a method to clone genes for wheat yield traits by sequencing RIL populations, identifying and validating 11 candidate genes from 77 QTLs.

Unraveling the Role of Urea Hydrolysis in Salt Stress Response during Seed Germination and Seedling Growth in Arabidopsis thaliana

This study shows that salt stress increases urea hydrolysis in Arabidopsis thaliana, raising cytoplasmic pH and inhibiting seed germination and seedling growth, challenging the traditional view of ammonium toxicity as the main cause.

Reductive dehalogenation by diverse microbes is central to biogeochemical cycles in deep-sea cold seeps

The paper investigates reductive dehalogenation in deep-sea cold seeps, identifying diverse RDases and their ecological role in biogeochemical cycles.

The stability of lower genital tract microbiota correlates with reproductive system function and in vitro fertilization and frozen embryo transfer outcomes in women with polycystic ovarian syndrome

This study investigates the relationship between lower genital tract microbiota and reproductive outcomes in PCOS patients, finding that higher Lactobacillus abundance correlates with better IVF-FET outcomes.

Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade

This study maps the NPR1 signaling hub and transcriptional cascade in plants using TurboID and greenCUT&RUN, revealing chromatin remodeling and histone demethylation in SA-induced resistance.

Genomic Revisitation and Reclassification of the Genus Providencia

This study reclassifies Providencia species using genomic data, identifies a new species, and reveals high antibiotic resistance gene prevalence.

Nuclear cytoophidia assembly represses transcriptional activity to control skeletal development and homeostasis

This study identifies nuclear cytoophidia as regulators of Impdh2 transcriptional activity, impacting skeletal development and homeostasis through effects on endochondral ossification and osteoclast function.

Unveiling unique microbial nitrogen cycling and novel nitrification drivers in coastal Antarctica

This study identifies unique microbial nitrogen cycling mechanisms in coastal Antarctica, highlighting the role of comammox Nitrospira in nitrification.

Enhancement of Protein Stability by Quenching Millisecond Conformational Dynamics

This study links millisecond conformational dynamics of ubiquitin to protein stability through alanine mutations affecting the C-terminal retracted state.

Rapid measurement and statistical ranking of leaf drought tolerance capacity in cotton

This study develops a Bayesian hierarchical model to rapidly measure and statistically rank cotton drought tolerance using leaf dry matter content and osmotic potential data from field trials.

A vast repertoire of secondary metabolites influences community dynamics and biogeochemical processes in cold seeps

This study investigates secondary metabolites in cold seep microbiomes using metagenomic, metatranscriptomic, and metabolomic data, revealing diverse biosynthetic gene clusters and their potential ecological roles.

Recombinant SARS-CoV-2 lacking initiating and internal methionine codons within ORF10 is attenuated in vivo

This study shows that a recombinant SARS-CoV-2 virus lacking ORF10 start and internal methionine codons is attenuated in hamsters, with reduced lower respiratory tract viral titre and increased reversion to wild-type.

CD4+ T cell senescence is associated with reduced reactogenicity in severe/critical COVID-19

The paper finds that higher levels of CD4+ T cell senescence in severe/critical COVID-19 patients correlate with reduced antibody responses and worse survival, especially in breakthrough infections.

H2O2 sulfenylates CHE linking local infection to establishment of systemic acquired resistance

The paper identifies H2O2-mediated sulfenylation of CHE as a mechanism for systemic acquired resistance in plants.

Proguanil and chlorhexidine augment the antibacterial activities of clarithromycin and rifampicin against Acinetobacter baumannii

This study shows that combining proguanil and chlorhexidine with clarithromycin or rifampicin enhances antibacterial activity against Acinetobacter baumannii in vitro and improves treatment outcomes in mice.