Author

F.-Y. Wei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Ogawa· 2 shared A. Inoue· 1 shared A. Iwama· 1 shared C. Nagiri· 1 shared F. K. Sano· 1 shared H. Akasaka· 1 shared H. H. Okamoto· 1 shared H. S. Oshima· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

A. Ogawa

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2 papers

Recent·Most cited

Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor

H. S. Oshima, A. Ogawa, F. K. Sano, H. Akasaka, T. Kawakami, H. H. Okamoto, A. Iwama, C. Nagiri, F.-Y. Wei, W. Shihoya, O. Nureki

The paper identifies a novel A3R-selective ligand and reveals structural insights into A3R activation, enabling structure-guided engineering of m6A-insensitive A3R for drug discovery.

bioRxiv · Mar 23, 2024 · PreprintBiophysics

Activation of the urotensin-II receptor by anti-COVID-19 drug remdesivir induces cardiomyocyte dysfunction

F.-Y. Wei, A. Inoue, A. Ogawa, S. Ohira, T. Ikuta, Y. Kato, S. Yanagida, Y. Ishii, Y. Kanda, M. Nishida

This study identifies remdesivir as a selective agonist of the urotensin-II receptor, linking its cardiotoxicity to receptor activation and genetic variants.

bioRxiv · Aug 8, 2022 · PreprintPharmacology & Toxicology