Molecular BiologyNature CommunicationsPeer-reviewed
A histone H4K20 methylation-mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Muhammad Shoaib, David Walter, Peter J. Gillespie…·Claus Storgaard Sørensen
The paper identifies a chromatin compaction threshold mediated by histone H4K20 methylation that limits DNA replication licensing in G1 phase to maintain genome integrity.
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