Molecular BiologyNature CommunicationsPeer-reviewed
PBRM1 directs PBAF to pericentromeres and protects centromere integrity
Karen A. Lane, Alison Harrod, Lillian Wu…·Jessica A. Downs
This study identifies PBAF as a protector of centromere and pericentromere structure, showing that PBRM1 loss leads to centromere fragility and therapeutic vulnerability.
10 citations