ImmunologybioRxivPreprint
An ER Retrieval-and-Release System Reveals Ligand-Independent Basal Signaling by Cell Surface TCRs
Claudia Juraske, Simon Beyer, Sara Hartmann…·Wolfgang Schamel
The paper develops an ER retrieval-and-release system to study ligand-independent basal TCR signaling, finding that surface TCRs generate distinct phosphorylation patterns compared to ligand-induced activation.
DOI 10.64898/2026.10.13.758962