Author

Fiona Pat

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:rat· 2 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Amanda Cimino· 2 shared Bridget J. CheniD· 2 shared Christine T. N. PhamiD· 2 shared David J. OttenheimeriD· 2 shared Erik D. HerzogiD· 2 shared Farshid GuilakiD· 2 shared Kurt M. FraseriD· 2 shared Omolabake Oyebamiji· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersSynthetic Biology

Amanda Cimino

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Programmable chronogenetic gene circuits for self-regulated circadian delivery of biologic drugs

Amanda Cimino, Fiona Pat, Omolabake Oyebamiji, Lara Pferdehirt, Christine T. N. Pham, Erik D. Herzog, Farshid Guilak

This study develops programmable gene circuits that deliver IL-1Ra in a circadian manner to protect cells from inflammation.

Journal of Controlled Release · Jun 18, 2025Peer-reviewedSynthetic Biology

Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways

Amanda Cimino, Fiona Pat, Omolabake Oyebamiji, Christine T. N. Pham, Erik D. Herzog, Farshid Guilak

This paper develops a dual-responsive synthetic gene circuit that combines circadian and inflammatory signals to enable timed and enhanced therapeutic drug delivery in inflammatory arthritis.

Journal of Biological Engineering · May 19, 2025Peer-reviewedSynthetic Biology

Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan‐Hernandez, Bridget J. Chen, Fiona Pat, David J. Ottenheimer, Patricia H. Janak

This study investigates how the central amygdala encodes and controls reward consumption in rats, showing that optogenetic stimulation enhances intake of preferred rewards but not less-preferred ones.

iScience · Apr 1, 2024Peer-reviewedNeuroscience

Contexts facilitate dynamic value encoding in the mesolimbic dopamine system

Kurt M. Fraser, Val L. Collins, Amy R. Wolff, David J. Ottenheimer, Kaisa N. Bornhoft, Fiona Pat, Bridget J. Chen, Patricia H. Janak, Benjamin T. Saunders

This study investigates how dopamine neurons in the mesolimbic system enable rapid revaluation of reward cues in changing environments using behavioral and neurophysiological methods in rats.

bioRxiv · Nov 5, 2023 · PreprintNeuroscience