Author
de Duve Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Nithya Balasundaram, Ayşegül Erdem, Azeem Sharda…·Nick van Gastel
This study identifies a unique metabolic plasticity mechanism in AML cells through protein S-acylation, which is inhibited by TOFA and a glutaminase inhibitor combination.
Hernán A. Tirado, Nithya Balasundaram, Jean Jacobs…·Nick van Gastel
This study investigates the role of EAAT1 in AML cell growth and therapy response, finding that EAAT1 inhibition does not impair AML growth or chemosensitivity.
Ayşegül Erdem, Séléna Kaye, Francesco Caligiore…·Nick van Gastel
This study shows that LDHA is essential for maintaining NAD+/NADH balance in AML cells, and its inhibition leads to cell death, suggesting it as a therapeutic target.