An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens
S. L. Tran, L. Lebreuilly, D. Cormontagne, S. Samson, T. B. To, R. Dervyn, A. Griesshammer, J. d. l. C. Zuluaga, L. Maier, T. Naas, S. Mura, J. Nicolas, D. Rognan, G. Andre, n. Ramarao
NM102 targets the Mfd protein to reduce bacterial evolvability and treat infections caused by antibiotic-resistant Gram-negative bacteria.
bioRxiv · Jan 22, 2024Microbiology