Author

A. Janiszewski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

V. Pasque· 2 shared A. C. Marques· 1 shared A. Jurisicova· 1 shared A. Murray· 1 shared A. Saitta· 1 shared A. Willig· 1 shared B. Bradshaw· 1 shared B. Thienpont· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

V. Pasque

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Author profile →

3 papers

Recent·Most cited

A deep learning approach for improved detection of homologous recombination deficiency from shallow genomic profiles

G. Andre, T. Coletta, C. Pozzorini, A. C. Marques, J. Bieler, R. Kempfer, C. Chong, A. Saitta, E. Smith, M. Macheret, A. Janiszewski, X. Bonilla, J. Bonet, H. Santos-Silva, M. Postl, , Z. Xu

This paper introduces a deep learning model to detect homologous recombination deficiency from shallow whole genome sequencing data, achieving high accuracy comparable to deeper sequencing methods.

bioRxiv · Jul 6, 2022 · PreprintCancer Biology

Defining totipotency using criteria of increasing stringency

E. Posfai, J. P. Schell, A. Janiszewski, I. Rovic, A. Murray, B. Bradshaw, T. Pardon, M. El Bakkali, I. Talon, N. De Geest, P. Kumar, S. K. To, S. Petropoulos, A. Jurisicova, V. Pasque, , J. Rossant

The paper defines totipotency using increasing stringency criteria and evaluates candidate cell types in mice, finding that expanded pluripotent states do not show higher totipotency than conventional embryonic stem cells under in vivo conditions.

bioRxiv · Mar 2, 2020 · PreprintCell Biology

Temporal resolution of global gene expression and DNA methylation changes in the final phases of reprogramming towards induced pluripotency.

M. Bartoccetti, X. Luo, B. van der Veer, R. Khoueiry, A. Janiszewski, J. Xu, C. Verfaillie, V. Pasque, B. Thienpont, K. P. Koh

This study identifies sequential activation of Tet1 and Oct4 during iPSC reprogramming, revealing distinct DNA demethylation waves and epigenetic dynamics critical for generating high-quality iPSCs.

bioRxiv · Feb 13, 2019 · PreprintCell Biology