Homologous mutations in β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation
C. Liu, A. Karabina, A. Meller, A. Bhattacharjee, C. J. Agostino, G. Bowman, K. M. Ruppel, J. A. Spudich, L. A. Leinwand
This study compares the effects of homologous mutations in three muscle myosin isoforms, finding divergent molecular impacts that correlate with disease severity.
bioRxiv · Jul 2, 2023 · PreprintBiophysics