Prevention of thrombocytopenia and thrombosis in heparin-induced thrombocytopenia (HIT) using deglycosylated KKO: A novel therapeutic?
A. Sarkar, S. Khandelwal, H. Kim, Y. Gruel, J. Rollin, G. D. Wool, G. M. Arepally, D. B. Cines, L. Rauova, M. Poncz
This paper demonstrates that deglycosylated KKO (DGKKO) can prevent and reverse thrombocytopenia and thrombosis in a HIT murine model.
bioRxiv · Oct 19, 2022 · PreprintCell Biology