BiochemistrybioRxiv
Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction
J. Sgrignani, V. Cecchinato, E. M. A. Fassi…·A. Cavalli
This study identifies a peptide inhibitor (HBP08) that disrupts the CXCL12/HMGB1 heterocomplex with high affinity, offering potential for treating chronic inflammatory diseases.
DOI 10.1021/acs.jmedchem.1c00852