Cell BiologybioRxiv
Endosomal cAMP production broadly impacts the cellular phosphoproteome
N. G. Tsvetanova, M. Trester-Zedlitz, B. W. Newton…·M. von Zastrow
The paper shows that endosomal cAMP production leads to distinct phosphoproteomic changes compared to plasma membrane cAMP, with a strong bias toward dephosphorylation by PP2A-B56{delta}.
DOI 10.1016/j.jbc.2021.100907