Porphyrin overdrive rewires pan-cancer cell metabolism
S. R. Adapa, G. Hunter, N. Amin, C. Marinescu, A. Borsky, E. Sagatys, S. Sebti, G. Reuther, G. Ferreira, R. Jiang
This study identifies porphyrin overdrive as a universal metabolic rewiring in cancer cells, showing its role in oncogenic growth and demonstrating a novel 'bait-and-kill' strategy to target it.
bioRxiv · Feb 18, 2022 · PreprintCancer Biology