Author

S. Sebti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. U. Shiloh· 2 shared Z. Zou· 2 shared A. Borsky· 1 shared B. Levine· 1 shared C. Marinescu· 1 shared E. Parks· 1 shared E. Sagatys· 1 shared G. Ferreira· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

M. U. Shiloh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CDKL5 regulates p62-mediated selective autophagy and host antiviral defense

J. W. Thinwa, Z. Zou, E. Parks, S. Sebti, K. Hui, V. Singh, Y. Wei, G. Urquhart, J. L. Jewell, J. K. Pfeiffer, B. Levine, T. A. Reese, M. U. Shiloh

This study identifies CDKL5 as a regulator of virophagy, showing it promotes p62-mediated autophagy of viral capsids and enhances antiviral defense.

bioRxiv · Sep 20, 2022Microbiology

Porphyrin overdrive rewires pan-cancer cell metabolism

S. R. Adapa, G. Hunter, N. Amin, C. Marinescu, A. Borsky, E. Sagatys, S. Sebti, G. Reuther, G. Ferreira, R. Jiang

This study identifies porphyrin overdrive as a universal metabolic rewiring in cancer cells, showing its role in oncogenic growth and demonstrating a novel 'bait-and-kill' strategy to target it.

bioRxiv · Feb 18, 2022 · PreprintCancer Biology

BECN1 F121A mutation increases autophagic flux in aged mice and improves aging phenotypes in an organ-dependent manner

S. Sebti, Z. Zou, M. U. Shiloh

This study shows that the Becn1F121A mutation enhances autophagic flux in aged mice, improving aging phenotypes in some organs but not others.

bioRxiv · Jan 12, 2022 · PreprintPhysiology