ImmunologybioRxiv
Protective efficacy of an orf virus-vector encoding the hemmagglutinin and the nucleoprotein of influenza A virus in swine
L. R. Joshi, D. Knudsen, P. Pineyro…·D. G. Diel
This study evaluates two recombinant orf viruses expressing hemagglutinin (HA) or HA and nucleoprotein (NP) of IAV-S in pigs, finding that OV-HA-NP provides better protection against swine influenza with reduced virus shedding and viral load.
DOI 10.3389/fimmu.2021.747574