Imaging ATP Consumption in Resting Skeletal Muscle: One Molecule at a Time
S. R. Nelson, A. Li, S. Beck-Previs, G. Kennedy, D. Warshaw
The paper uses super-resolution microscopy to image single ATP molecule consumption in relaxed rat soleus muscle sarcomeres, revealing two distinct hydrolysis rates with the slower rate localized to the C-zone where MyBP-C is present.
bioRxiv · May 27, 2020Biophysics