Author

G. L. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Saha· 2 shared M. A. Mandell· 2 shared B. Phinney· 1 shared E. Sjottem· 1 shared G. Evjen· 1 shared H. Olsvik· 1 shared M. L. Paffett· 1 shared M. R. Salemi· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

B. Saha

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Author profile →

2 papers

Recent·Most cited

TBK1 is ubiquitinated by TRIM5alpha to assemble mitophagy machinery

B. Saha, H. Olsvik, G. L. Williams, S. Oh, G. Evjen, E. Sjottem, M. A. Mandell

The paper shows TRIM5 ubiquitinates TBK1 to assemble mitophagy machinery on damaged mitochondria, essential for both Parkin-dependent and independent mitophagy.

bioRxiv · Oct 19, 2023Cell Biology

Interactomic analysis reveals a new homeostatic role for the HIV restriction factor TRIM5α in mitophagy

B. Saha, M. R. Salemi, G. L. Williams, M. L. Paffett, B. Phinney, M. A. Mandell

The paper identifies a novel role for TRIM5α in mitophagy, showing it regulates mitochondrial quality control and prevents cell death under mitochondrial stress.

bioRxiv · Aug 20, 2021Cell Biology