Cell BiologybioRxiv
Interactomic analysis reveals a new homeostatic role for the HIV restriction factor TRIM5α in mitophagy
B. Saha, M. R. Salemi, G. L. Williams…·M. A. Mandell
The paper identifies a novel role for TRIM5α in mitophagy, showing it regulates mitochondrial quality control and prevents cell death under mitochondrial stress.
DOI 10.1016/j.celrep.2022.110797