Interleukin-10 knockout mice do not reliably exhibit macroscopic inflammation: a natural history endoscopic surveillance study
S. Y. Kim, J. Park, G. Leite, M. Pimentel, A. Rezaie
This study tracks endoscopic changes in IL-10 knockout mice and finds that 40% do not develop colitis, with all cases resolving spontaneously.
bioRxiv · Dec 18, 2021 · PreprintImmunology