Author

G. M. Diffee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. S. Roberts· 2 shared P. Balasubramanian· 2 shared R. J. Colman· 2 shared Y. Ge· 2 shared A. B. Smith· 1 shared A. E. Schaar· 1 shared A. Greenman· 1 shared D. W. Lamming· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

D. S. Roberts

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mass spectrometry-based multi-omics identifies metabolic signatures of sarcopenia in rhesus monkey skeletal muscle

M. R. Pergande, K. J. Osterbauer, K. M. Buck, D. S. Roberts, N. N. Wood, P. Balasubramanian, M. W. Mann, K. Rossler, G. M. Diffee, R. J. Colman, R. M. Anderson, Y. Ge

This study uses mass spectrometry-based multi-omics to identify metabolic signatures of sarcopenia in rhesus monkey skeletal muscle, revealing age-related changes in energy metabolism and muscle function.

bioRxiv · Jul 31, 2023 · PreprintBiochemistry

High Sensitivity Top-down Proteomics Captures Single Muscle Cell Heterogeneity in Large Proteoforms

J. A. Melby, K. A. Brown, Z. R. Gregorich, D. S. Roberts, E. A. Chapman, L. E. Ehlers, Z. Gao, E. J. Larson, Y. Jin, J. Lopez, J. Hartung, Y. Zhu, D. Wang, W. Guo, G. M. Diffee, Y. Ge

This study develops a sensitive top-down proteomics method to analyze large proteoforms in single muscle cells, revealing heterogeneity and linking it to muscle fiber types.

bioRxiv · Dec 29, 2022 · PreprintBiochemistry

Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice

P. Balasubramanian, A. E. Schaar, G. E. Gustafson, A. B. Smith, P. R. Howell, A. Greenman, S. Baum, R. J. Colman, D. W. Lamming, G. M. Diffee, R. Anderson

AdipoRon, an adiponectin receptor agonist, improves skeletal muscle function in aged mice by enhancing mitochondrial activity and metabolism, with effects observed in both mice and nonhuman primates.

bioRxiv · Sep 16, 2021Physiology