Author

G. Nicolas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

A. Danoff· 1 shared A. Moustapha· 1 shared A. Rovelet-Lecrux· 1 shared A. Saric· 1 shared C. M. Rondelli· 1 shared C. Schramm· 1 shared D. Campion· 1 shared F. Sureau· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Danoff

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

A. Rovelet-Lecrux, S. Feuillette, L. Miguel, C. Schramm, S. Pernet, I. Segalas-Milazzo, L. Guilhaudis, S. Rousseau, G. Riou, T. Frebourg, D. Campion, G. Nicolas, M. Lecourtois

This paper identifies SORL1 missense variants that impair SorLA maturation and trafficking, leading to increased Aβ secretion and linking these variants to Alzheimer's disease pathophysiology.

bioRxiv · Jun 18, 2021Cell Biology

CLPX regulates erythroid heme synthesis by control of mitochondrial heme synthesis enzymes and iron utilization

C. M. Rondelli, M. Perfetto, A. Danoff, H. Bergonia, S. Gillis, G. Nicolas, H. Puy, R. West, J. D. Phillips, Y. Y. Yien

This study shows CLPX regulates erythroid heme synthesis by controlling ALAS2 stability, PPOX activity, and iron metabolism, with its role not conserved across eukaryotes.

bioRxiv · Sep 9, 2020 · PreprintBiochemistry

Iron chelation by curcumin suppress both curcumin-induced autoghagy and cell death together with iron overload neoplastic transformation

N. E. Rainey, A. Moustapha, A. Saric, G. Nicolas, F. Sureau, P. X. Petit

This study investigates how curcumin affects iron overload-induced autophagy, apoptosis, and tumorigenesis in liver cells.

bioRxiv · Aug 2, 2019 · PreprintCell Biology