ImmunologybioRxivPreprint
Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells
Z. H. Walsh, P. Shah, N. Kothapalli…·B. Izar
This study uses base editing to screen for variants affecting T cell anti-tumor functions, identifying mutations that enhance tumor elimination with minimal off-target effects.
DOI 10.1101/2023.12.13.571465