mTOR signaling controls the formation of smooth muscle cell-derived intimal fibroblasts during vasculitis.
A. Stock, S. Parsons, J. Hansen, D. B. D'Silva, G. Starkey, A. Fayed, X. Y. Lim, R. D'Costa, C. L. Gordon, I. P. Wicks
This study identifies mTOR signaling as essential for the formation of SMC-derived intimal fibroblasts in vasculitis, offering a therapeutic target for vascular remodeling.
bioRxiv · Dec 15, 2023 · PreprintCell Biology