Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells
S. Conti, V. Venturini, A. Canellas-Socias, C. Cortina, J. F. Abenza, C. S.-O. Attolini, E. M. Guerra, C. K. Xu, J. H. Li, L. Rossetti, G. Stassi, P. Roca-Cusachs, A. Diz-Munoz, V. Ruprecht, J. Guck, , X. Trepat
This study identifies mechanical phenotype differences between LGR5+ and LGR5- colorectal cancer cells, linking them to membrane to cortex attachment proteins and metastatic potential.
bioRxiv · Dec 4, 2023Cancer Biology