Author

Garrett Klokman

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Yubin Qiu· 3 shared Christopher W. WilsoniD· 2 shared Ganesh PrasannaiD· 2 shared John T. Demirs· 2 shared Jorge ArandaiD· 2 shared Junzheng YangiD· 2 shared Magali Saint‐GenieziD· 2 shared Michael TwarogiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Yubin Qiu

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3 papers

Recent·Most cited

Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation

Kyle Bond, Garrett Klokman, YongYao Xu, Xiaoqiu Wu, Joshua Schustak, Jorgi Mandelbaum, Michael Twarog, Hongwei Han, Fumiaki Aihara, Mary-Kate Paulina, Matthew Coble, Christopher Hayden, Jean-René Galarneau, John T. Demirs, Yubin Qiu, , Yi Bao

This study shows dsRNA triggers RIG-I signaling, leading to inflammation and RPE degeneration in AMD, with implications for pathogenesis.

The FASEB Journal · Aug 15, 2025Peer-reviewedCell Biology

Identification of cellular and molecular risk signatures for progression to late-stage age-related macular degeneration using the 9-step Minnesota Grading System

Chia Ling Huang, Yubin Qiu, John T. Demirs, Xiaoqiu Wu, Michael Twarog, Omar Delgado, Maura A. Crowley, Natasha M. Buchanan, Nhi Vo, Lin Fan, Yanqun Wang, Junzheng Yang, Thomas R. Vollmer, Garrett Klokman, Sandra Jose, , Sha-Mei Liao

This study uses bulk RNA sequencing on postmortem human eye tissue to identify gene and pathway changes associated with progression from intermediate to late-stage AMD, highlighting potential therapeutic targets.

bioRxiv · Jul 10, 2025 · PreprintNeuroscience

A spontaneous mutation in ADIPOR1 causes retinal degeneration in mice

Junzheng Yang, Natasha M. Buchanan, Erika Urbano de Lima, Angela Banks, Valentin M. Sluch, Lin Fan, Barrett D. Leehy, Ivana A. Arellano, Yubin Qiu, Garrett Klokman, Shawn M. Hanks, Joanna Vrouvlianis, Vanessa Davis, Chung-Yeh Wu, Aaron D. Danilack, Dennis S. Rice

A mutation in AdipoR1 causes retinal degeneration in a subset of Cfh-/- mice, suggesting a genetic interaction between Cfh and AdipoR1.

bioRxiv · Jun 6, 2024 · PreprintNeuroscience