Author

Jorge Aranda

Novartis (Switzerland)ORCID 0000-0002-9775-5842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher W. WilsoniD· 2 shared Ganesh PrasannaiD· 2 shared Garrett Klokman· 2 shared John T. Demirs· 2 shared Magali Saint‐GenieziD· 2 shared Michael TwarogiD· 2 shared Xiaoqiu Wu· 2 shared Yubin Qiu· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCell Biology

Christopher W. WilsonORCID

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2 papers

Recent·Most cited

Cell BiologyThe FASEB JournalPeer-reviewedAug 15, 2025

Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation

Kyle Bond, Garrett Klokman, YongYao Xu…·Yi Bao

This study shows dsRNA triggers RIG-I signaling, leading to inflammation and RPE degeneration in AMD, with implications for pathogenesis.

1 citation

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 10, 2025

Identification of cellular and molecular risk signatures for progression to late-stage age-related macular degeneration using the 9-step Minnesota Grading System

Chia Ling Huang, Yubin Qiu, John T. Demirs…·Sha-Mei Liao

This study uses bulk RNA sequencing on postmortem human eye tissue to identify gene and pathway changes associated with progression from intermediate to late-stage AMD, highlighting potential therapeutic targets.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky