Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling
Arianna Coppola, Filomena Amoroso, Federica Saracino…·Annalisa Fico
This study identifies T-UCstem1 as a key lncRNA regulating gastruloid development through DKK1-dependent modulation of WNT signaling, affecting anteroposterior axis extension and cellular identity.