BiochemistryJournal of Proteome ResearchPeer-reviewed
Deep Profiling of Plasma Proteoforms with Engineered Nanoparticles for Top-down Proteomics
Che‐Fan Huang, Michael A. R. Hollas, Aniel Sánchez…·Neil L. Kelleher
This study uses engineered nanoparticles to enrich low-abundant proteins in human plasma, enabling top-down proteomics to detect proteoforms at lower concentrations and expand proteome depth.
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