Multiscale Analysis of PNPLA2 and PNPLA3 Membrane Targeting
Amit Kumar, Grace Teskey, Emilio P. Mottillo, Yu‐ming M. Huang
This study investigates how PNPLA2 and PNPLA3 bind to ER and LD membranes using simulations and microscopy, revealing distinct binding modes and their impact on catalytic activity.
bioRxiv · Feb 14, 2026 · PreprintBiophysics