Author

Graeme M. Sloan

University of Dundee

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

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César Mendoza-MartíneziD· 1 shared David HorniD· 1 shared Markéta NovotnáiD· 1 shared Melanie C. RidgwayiD· 1 shared Michele TintiiD· 1 shared Simone AltmanniD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMicrobiology

César Mendoza-MartínezORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintNov 26, 2025

Acoziborole resistance associated mutations in trypanosome CPSF3

Melanie C. Ridgway, Markéta Novotná, César Mendoza-Martínez…·David Horn

The paper identifies mutations in trypanosome CPSF3 that confer resistance to acoziborole, a drug targeting RNA processing, and explains the molecular mechanism of resistance through computational modeling.

DOI 10.1101/2025.11.26.690711

humanexperimental assay

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