Author

Graham Booker

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Anita E. GrigoriadisiD· 2 shared Gregory E VergheseiD· 2 shared Sarah E. PinderiD· 2 shared Aasiyah Oozeer· 1 shared Anca Mera· 1 shared Anthony Baptista· 1 shared Cathrin BriskeniD· 1 shared Cheryl Gillet· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPathology

Anita E. GrigoriadisORCID

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Author profile →

3 papers

Recent·Most cited

HIF-1 regulated TPM3 links hypoxia to motility and invasion beyond the hypoxic fraction in triple-negative breast cancer

Chumin Zhou, Jack T. Crusher, Kenneth Friesen, Sophie A. Twigger, Eduard Petrosyan, Graham Booker, Priya Samuel, Eileen E. Parkes, Ester M. Hammond

This study identifies TPM3 as a HIF-1-regulated protein that enhances hypoxic TNBC cell motility and invasion, and shows its potential as a therapeutic target.

npj Breast Cancer · Mar 14, 2026Peer-reviewedCancer Biology

Normal Breast Tissue (NBT)-Classifiers: Advancing Compartment Classification in Normal Breast Histology

Siyuan Chen, Mario Parreno-Centeno, Graham Booker, Gregory E Verghese, Fathima Sumayya Mohamed, Salim Arslan, Pahini Pandya, Aasiyah Oozeer, Marcello D’Angelo, Rachel Barrow‐McGee, Rachel L. Nelan, Marcelo Sobral-Leite, Fabio De Martino, Cathrin Brisken, Matthew John Smalley, , Anita E. Grigoriadis

CNN patch classifiers trained only on normal breast H&E slides label epithelium, stroma and adipocytes with AUCs of 0.98–1.00 on three external cohorts and feed a lobule-detection pipeline.

npj Breast Cancer · Feb 9, 2026Peer-reviewedPathology✦ In-depth digest

SMART: A Spatio-Molecular Atlas of Response Trajectories in Triple-Negative Breast Cancer

Isobelle Wall, Anthony Baptista, Jelmar Quist, Holly Rafique, Mengyuan Li, Lucy Ryan, Gregory E Verghese, Stefania Marcotti, Thomas A. Phillips, Claudia Owczarek, Signe Clausen, Trine Tramm, Graham Booker, Anca Mera, Jasmine Timbres, , Anita E. Grigoriadis

The paper introduces SMART, a spatio-molecular atlas of TNBC response trajectories, revealing distinct epithelial archetypes and tumor-immune microenvironments associated with treatment response and prognosis.

bioRxiv · Aug 27, 2025 · PreprintCancer Biology