Author

Graham Wells

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Adam Cribbs· 1 shared Adam P. CribbsiD· 1 shared Adrienne M Flanagan· 1 shared Anthony Tumber· 1 shared Anvesha Saxena· 1 shared Catrine Johannson· 1 shared Charlotte PalmeriD· 1 shared Clarence YappiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adam Cribbs

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The KDM6 histone demethylase inhibitor GSK-J4 induces metal and stress responses in multiple myeloma cells

Adam P. Cribbs, Edward S. Hookway, Clarence Yapp, KaHing Che, James E. Dunford, Karina Gutheridge, Charlotte Palmer, Federica Lari, Graham Wells, Martin Philpott, Peter Cain, Deborah H. Brotherton, Eleanor Calcutt, Anvesha Saxena, Hal Drakesmith, , Udo C. T. Oppermann

This study shows GSK-J4, a KDM6 inhibitor, induces metal and stress responses in multiple myeloma cells by increasing intracellular Zn2+ and activating metallothionein gene expression.

RSC Chemical Biology · Jan 1, 2026Peer-reviewedCell Biology

Epigenetic inactivation of oncogenic brachyury (TBXT) by H3K27 histone demethylase controls chordoma cell survival

Lucia Cottone, Edward S Hookway, Adam Cribbs, Graham Wells, Patrick Lombard, Lorena Ligammari, Anthony Tumber, Roberto Tirabosco, Fernanda Amary, Tamas Szommer, Catrine Johannson, Paul E Brennan, Nischalan Pillay, Udo Oppermann, Adrienne M Flanagan

This study shows that inhibiting H3K27 demethylases reduces TBXT expression and kills chordoma cells by altering epigenetic marks and gene expression.

bioRxiv · Oct 1, 2018 · PreprintCancer Biology