Author
Royal National Orthopaedic HospitalORCID 0000-0003-0671-7531Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Hillary Elrick, Carolin M. Sauer, Jose Espejo Valle-Inclán…·Isidro Cortés‐Ciriano
SAVANA improves detection of somatic structural variants and copy number aberrations in cancer using long-read sequencing with higher sensitivity and specificity than existing tools.
Jose Espejo Valle-Inclán, Solange De Noon, Katherine E. Trevers…·Isidro Cortés‐Ciriano
This study identifies chromothripsis and a novel LTA chromothripsis mechanism driving genome complexity and evolution in osteosarcoma, with prognostic implications for high-grade tumors.
William C. H. Cross, Iben Lyskjær, Tom Lesluyes…·Adrienne Margaret Flanagan
The paper presents a genetic model of central chondrosarcoma using genomic and epigenomic data to identify mutations and methylation patterns associated with patient outcomes.
Matthew W. Fittall, Iben Lyskjær, Peter Ellery…·Adrienne Margaret Flanagan
This study identifies genomic and methylation patterns associated with benign metastases and malignant transformation in giant cell tumour of bone.
Lucia Cottone, Edward S Hookway, Adam Cribbs…·Adrienne M Flanagan
This study shows that inhibiting H3K27 demethylases reduces TBXT expression and kills chordoma cells by altering epigenetic marks and gene expression.