A distinctive subset of microglia positioned at the paraventricular zone are dedicated to cleaning the cerebrospinal fluid
Guoyang Zhou, Jian He, Baojie Mao, Guo Cheng, Rui Zhang, Qiang Wang, Xiaoli Liu, Jiaxin Zheng, Ming Wang, Zhao Li, Peng D. Shi, Xiao Z. Shen, Shu Wan
The paper identifies a subset of microglia in the paraventricular zone that clean cerebrospinal fluid by phagocytosing exogenous particles and prevents ventriculomegaly when removed.
bioRxiv · Feb 23, 2025 · PreprintImmunology