The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells
S. Vipat, D. Gupta, S. Jonchhe, H. Anderspuk, E. Rothenberg, T. N. Moiseeva
This study investigates the non-catalytic role of POLE1 in DNA replication initiation in human cells, finding that its C-terminal domain can rescue replication initiation through interaction with POLE2.
bioRxiv · Mar 21, 2022Cell Biology