Author

E. Rothenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Organism:human· 3 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Bekesi· 1 shared A. N. Kousholt· 1 shared A. Poti· 1 shared B. G. Vertessy· 1 shared B. Gyorffy· 1 shared C. Gemma· 1 shared D. Gupta· 1 shared D. Szuts· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Bekesi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells

S. Vipat, D. Gupta, S. Jonchhe, H. Anderspuk, E. Rothenberg, T. N. Moiseeva

This study investigates the non-catalytic role of POLE1 in DNA replication initiation in human cells, finding that its C-terminal domain can rescue replication initiation through interaction with POLE2.

bioRxiv · Mar 21, 2022Cell Biology

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

J. Jimenez-Sainz, J. Mathew, G. Moore, S. Lahiri, J. Garbarino, J. P. Eder, E. Rothenberg, R. B. Jensen

This study evaluates three BRCA2 missense variants, showing two disrupt RAD51 binding and DNA repair, while the third is functional and benign.

bioRxiv · Sep 24, 2021Cancer Biology

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments

H. L. Palinkas, A. Bekesi, G. Rona, L. Pongor, G. Tihanyi, E. Holub, A. Poti, C. Gemma, S. Ali, M. J. Morten, E. Rothenberg, M. Pagano, D. Szuts, B. Gyorffy, B. G. Vertessy

The paper investigates genome-wide uracil distribution changes in human cells after chemotherapy, finding drug-induced shifts toward active genomic regions.

bioRxiv · Mar 4, 2020Biochemistry

Nav1.5 single-molecule localization reveals different reorganization modes at cardiomyocyte domains

S. Vermij, J.-S. Rougier, E. Agullo-Pascual, E. Rothenberg, M. Delmar, H. Abriel

The paper uses single-molecule localization microscopy to study Nav1.5 localization in different cardiomyocyte domains and finds site-specific redistribution in disease models.

bioRxiv · Nov 21, 2019 · PreprintPhysiology

PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps

K. Cong, A. N. Kousholt, M. Peng, N. J. Panzarino, W. T. C. Lee, S. Nayak, J. Krais, J. Calvo, M. Bere, E. Rothenberg, N. Johnson, J. Jonkers, S. Cantor

This study shows PARPi sensitivity in BRCA-deficient cells arises from replication-associated ssDNA gaps, not replication speed.

bioRxiv · Sep 25, 2019Cancer Biology