Cell BiologybioRxiv
The non-catalytic role of DNA polymerase epsilon in replication initiation in human cells
S. Vipat, D. Gupta, S. Jonchhe…·T. N. Moiseeva
This study investigates the non-catalytic role of POLE1 in DNA replication initiation in human cells, finding that its C-terminal domain can rescue replication initiation through interaction with POLE2.
DOI 10.1038/s41467-022-34911-4