Structural dissection of the first events following membrane binding of the islet amyloid polypeptide
L. Khemtemourian, H. Fatafta, B. Davion, S. Lecomte, S. Castano, B. Strodel
This study investigates the early molecular events of IAPP binding to lipid membranes using spectroscopy, microscopy, and simulations, revealing how residue 18 affects structure and aggregation.
bioRxiv · Dec 14, 2021Biophysics