Author

S. Lecomte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Khemtemourian· 2 shared A. Bauza· 1 shared A. Frontera· 1 shared A. Vial· 1 shared A. Walrant· 1 shared B. Davion· 1 shared B. Strodel· 1 shared C. Feuillie· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

L. Khemtemourian

Mutual co-authors in cluster

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3 papers

Recent·Most cited

N-formylation modifies membrane damage associated to PSMα3 interfacial fibrillation

L. Bonnecaze, K. Jumel, A. Vial, L. Khemtemourian, C. Feuillie, M. Molinari, S. Lecomte, M. Mathelie-Guinlet

This study shows N-formylation of PSM3 affects its membrane interactions and self-assembly, leading to membrane damage through intermediate protofibrillar entities.

bioRxiv · Feb 27, 2024Biophysics

Structural dissection of the first events following membrane binding of the islet amyloid polypeptide

L. Khemtemourian, H. Fatafta, B. Davion, S. Lecomte, S. Castano, B. Strodel

This study investigates the early molecular events of IAPP binding to lipid membranes using spectroscopy, microscopy, and simulations, revealing how residue 18 affects structure and aggregation.

bioRxiv · Dec 14, 2021Biophysics

Ionpair-π interactions favor cell penetration of arginine/tryptophan-rich cell-penetrating peptides

A. Walrant, A. Bauza, C. Girardet, I. D. Alves, S. Lecomte, F. Illien, S. Cardon, N. Chaianantakul, M. Pallerla, F. Burlina, A. Frontera, S. Sagan

This study investigates how Trp and facial amphiphilicity affect CPP uptake, finding that Trp enhances uptake in GAG-expressing cells and that facial amphiphilicity is not essential.

bioRxiv · Jul 28, 2019Biochemistry