Cancer BiologybioRxiv
Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma
E. De Crignis, S. Romal, F. Carofiglio…·T. Mahmoudi
This paper establishes human liver organoids as a model for HBV infection and HCC, showing they support viral replication, produce infectious HBV, and exhibit cancer-related gene signatures.