Functional identification of soluble uric acid as an endogenous inhibitor of CD38
S. Wen, H. Arakawa, S. Yokoyama, Y. Shirasaka, H. Higashida, I. Tamai
This study identifies soluble uric acid as an endogenous inhibitor of CD38, showing it limits NAD+ degradation and suppresses inflammation in mice.
bioRxiv · Jun 3, 2023Immunology