Author

H. Koss

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Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. G. Palmer· 1 shared A. Stainthorp· 1 shared B. H. Honig· 1 shared C. Molina-Paris· 1 shared C. Seiler· 1 shared C.-C. Lin· 1 shared E. A. Miska· 1 shared J. E. Ladbury· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. G. Palmer

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2 papers

Recent·Most cited

Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

C.-C. Lin, K. M. Suen, P.-A. Jeffrey, L. Wieteska, A. Stainthorp, C. Seiler, H. Koss, C. Molina-Paris, E. A. Miska, Z. Ahmed, J. E. Ladbury

This study shows that RTKs form liquid-liquid phase-separated states with downstream effectors to enhance signaling fidelity.

Molecular Cell · Mar 1, 2022Peer-reviewedCell Biology

Cadherin-11 dimerization multi-site kinetics: combined partial unfolding and strand-swapping

H. Koss, B. H. Honig, L. S. Shapiro, A. G. Palmer

The paper uses NMR spectroscopy to study the dimerization mechanism of Cadherin-11, revealing coupled folding and strand-swapping involving Trp2 and Trp4 residues.

bioRxiv · Dec 21, 2020Biophysics