BiophysicsbioRxiv
Modeling Resistance and Recurrence Patterns of Combined Targeted- Chemoradiotherapy Predicts Benefit of Shorter Induction Period
D. M. McClatchy, H. Willers, A. N. Hata…·C. Grassberger
The paper develops a bio-mathematical model to simulate recurrence patterns in lung cancer under combined targeted therapy and CRT, showing that long induction periods may reduce the effectiveness of adjuvant therapy.
DOI 10.1158/0008-5472.can-19-3883