Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier.
J. Kim, M. Hetman, E. M. Hattab, J. Joiner, B. Alejandro, H. Schroten, H. Ishikawa, D. Chung
This study identifies that Zika virus infects pericytes in the choroid plexus and crosses the blood-CSF barrier to enter the CNS, with CSF neutralization reducing brain infection.
PLOS Pathogens · May 1, 2020Peer-reviewedMicrobiology