Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability
R. G. Parra, M. J. Przybilla, M. Simovic, H. Susak, M. Ratnaparkhe, J. K. Wong, V. Koerber, P. Mallm, M. Sill, T. Kolb, R. Kumar, N. Casiraghi, D. R. Ghasemi, K. K. Maass, K. W. Pajtler, , A. Ernst
This study analyzes single-cell multi-omics data from medulloblastoma to explore genomic and transcriptomic impacts of chromothripsis and its subclonal variation.
bioRxiv · Jun 25, 2021 · PreprintCancer Biology