Integrative analysis of nanopore direct RNA sequencing data reveals a role of PUS7-dependent pseudouridylation in regulation of m6A and m5C modifications
M. Bansal, A. Kundu, A. Gupta, J. Ding, A. Gibson, S. V. RudraRaju, S. Sudarshan, H.-F. Ding
The paper introduces NanoPsiPy, a pipeline for detecting pseudouridylation sites using nanopore sequencing, and shows PUS7-dependent pseudouridylation affects m6A and m5C levels.
bioRxiv · Jan 31, 2024 · PreprintCancer Biology