A. Kundu

Integrative analysis of nanopore direct RNA sequencing data reveals a role of PUS7-dependent pseudouridylation in regulation of m6A and m5C modifications

The paper introduces NanoPsiPy, a pipeline for detecting pseudouridylation sites using nanopore sequencing, and shows PUS7-dependent pseudouridylation affects m6A and m5C levels.

Formation of clathrin-pits and ATP-independent cholesterol-dependent tubules initiates mechano-regulation on de-adhesion.

This study shows that during de-adhesion, cells use endocytosis to regulate membrane fluctuations, with dynamin-dependent and cholesterol-dependent ATP-independent mechanisms contributing.

Saccharomyces cerevisiae DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins

This study identifies yeast DJ-1 orthologs as glycation repair enzymes that protect genome integrity and mitochondrial function against reactive carbonyl species.

TGF-B signaling suppresses TCA cycle metabolism in renal cancer.

This study shows that TGF-β signaling suppresses TCA cycle enzyme expression in renal cancer, leading to reduced mitochondrial metabolism and tumor growth.

Active microrheology using pulsed optical tweezers to probe viscoelasticity of Lamin A towards diagnosis of laminopathies

This study uses active microrheology with optical tweezers to measure viscoelastic changes in lamin A mutants, linking structural alterations to disease mechanisms in laminopathies.

Piriformospora indica employs hosts putrescine for growth promotion in plants

This study identifies putrescine as a key metabolite mediating growth promotion by Piriformospora indica in plants through ADC pathway activation and hormone regulation.

Turanose induced WOX5 restores symbiosis in the Medicago truncatula cytokinin perception mutant cre1

Turanose and WOX5 overexpression restore symbiosis in the cytokinin perception mutant cre1 by modulating auxin conjugate hydrolase MtIAR33.

Transcriptomic analysis with the progress of symbiosis in ‘crack-entry’ legume Arachis hypogaea highlights its contrast with ‘infection thread’ adapted legumes

This study compares the transcriptomic profiles of symbiosis progression in crack-entry legume Arachis hypogaea with infection thread-adapted legumes, identifying key gene expression differences.

Small Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein

The paper investigates how small molecules affect the conformational dynamics and aggregation of alpha synuclein, showing additive effects of an inhibitor and facilitator on different stages of aggregation.