Author

S. Sudarshan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Kundu· 2 shared J. Hogins· 2 shared L. Reitzer· 2 shared P. E. Zimmern· 2 shared A. Gibson· 1 shared A. Gupta· 1 shared D. S. Chandrashekar· 1 shared G. Brinkley· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

A. Kundu

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Author profile →

4 papers

Recent·Most cited

Integrative analysis of nanopore direct RNA sequencing data reveals a role of PUS7-dependent pseudouridylation in regulation of m6A and m5C modifications

M. Bansal, A. Kundu, A. Gupta, J. Ding, A. Gibson, S. V. RudraRaju, S. Sudarshan, H.-F. Ding

The paper introduces NanoPsiPy, a pipeline for detecting pseudouridylation sites using nanopore sequencing, and shows PUS7-dependent pseudouridylation affects m6A and m5C levels.

bioRxiv · Jan 31, 2024 · PreprintCancer Biology

TGF-B signaling suppresses TCA cycle metabolism in renal cancer.

H. Nam, A. Kundu, S. Karki, G. Brinkley, D. S. Chandrashekar, R. L. Kirkman, J. Liu, M. V. Liberti, J. W. Locasale, T. Mitchell, S. Varambally, S. Sudarshan

This study shows that TGF-β signaling suppresses TCA cycle enzyme expression in renal cancer, leading to reduced mitochondrial metabolism and tumor growth.

bioRxiv · Feb 19, 2021 · PreprintCancer Biology

The Nutrient and Energy Pathway Requirements for Surface Motility of Nonpathogenic and Uropathogenic Escherichia coli

S. Sudarshan, J. Hogins, S. Ambagaspitiye Gedara, P. E. Zimmern, L. Reitzer

The paper examines the nutrient and pathway requirements for surface motility in nonpathogenic and uropathogenic E. coli strains, finding differences in metabolic dependencies based on appendage type.

bioRxiv · Aug 12, 2020Microbiology

FIMBRIAE AND FLAGELLA MEDIATED SURFACE MOTILITY AND THE EFFECT OF GLUCOSE ON NONPATHOGENIC AND UROPATHOGENIC ESCHERICHIA COLI

S. Ambagaspitiye, S. Sudarshan, J. Hogins, P. McDill, N. J. De Nisco, P. E. Zimmern, L. Reitzer

This study compares surface motility in nonpathogenic and uropathogenic E. coli, showing differences in appendage use and glucose effects on flagella synthesis.

bioRxiv · Nov 13, 2019 · PreprintMicrobiology