Embryonic Mast Cells Arise from Cpa3-expressing Precursors Independent of Granulocyte-Monocyte Progenitors
Wei Ma, Huifang Chen, Fei Gao, Han Zhao, Ningbo Wu, Shuangyan Zhang, Yiwen Zhu, Xu Zijian, Yu Lan, Bing Liu, Youqiong Ye, Zhaoyuan Liu, Florent Ginhoux, Bing Su
This study identifies Cpa3-expressing precursors as the source of embryonic mast cells, independent of granulocyte-monocyte progenitors, using single-cell RNA sequencing and genetic fate mapping.
Science China Life Sciences · May 22, 2025Peer-reviewedImmunology